A randomized controlled trial was conducted in cardiology department and smoking cessation
center of University Hospital of Monastir (Tunisia). All smokers Hospitalized for ACS were
included. Participants were randomly assigned to either group "A", initiating Nicotine
replacement therapy (NRT) in intra-hospitalization or a control group "B" that received NRT
after hospital discharge. The end point assessment was smoking abstinence at 24 weeks
following randomization, defined as self-reported abstinence in the past week before the 24
week clinic visit confirmed by a measured exhaled carbon monoxide ≤8 ppm. Data were analyzed
by intention to treat.