Overview
Skeletal Muscle and Adipose Tissue Study
Status:
Active, not recruiting
Active, not recruiting
Trial end date:
2022-04-01
2022-04-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
The purpose of this research study is to compare the current standard of care for prophylactic Cefazolin administered every 3 hours intravenously with continuous infusion of Cefazolin during pediatric spinal surgery.Phase:
Phase 4Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
University of FloridaTreatments:
Cefazolin
Dialysis Solutions
Criteria
Inclusion Criteria:- Diagnosis of idiopathic scoliosis
- Planned posterior spinal fusion surgery (PSFS)
- Age: 12-20 years old
- American Society of Anesthesiology status I or II undergoing posterior spinal fusion
for at least 6 levels
- No known allergy to cefazolin
Exclusion Criteria:
- Known allergy to cefazolin
- Anatomical or other abnormalities that precluded insertion of a microdialysis catheter
into the selected paraspinal muscle
- Known renal or hepatic insufficiency or failure