Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors
Status:
Recruiting
Trial end date:
2023-09-01
Target enrollment:
Participant gender:
Summary
Primary objective of the study is to improve the 2-year progression-free survival in children
with high-risk solid tumors who are administered a maintenance regimen with continuous
sirolimus administered on a backbone of metronomic chemotherapy following the completion of
"standard" therapy, as compared to high-risk solid tumor patients treated with observation
alone following completion of "standard" therapy.