Sirolimus for Cowden Syndrome With Colon Polyposis
Status:
Recruiting
Trial end date:
2023-08-01
Target enrollment:
Participant gender:
Summary
Colon polyposis (the presence of multiple colon polyps) is very common with Cowden syndrome,
as over 60% of patients have 50 or more polyps. In a previous clinical trial, some
participants had reduction in the number of colon polyps with the use of the medication
sirolimus for a very short time period. This study is investigating sirolimus and its effect
on the number of colon polyps in patients with Cowden syndrome and polyposis over a 1 year
period.