Overview

Single-dose of Nalmefene to Modulate Neural Alcohol Cue Reactivity

Status:
Terminated
Trial end date:
2016-05-01
Target enrollment:
Participant gender:
Summary
The aim of this study is to use functional Magnetic Resonance Imaging (fMRI) to measure neural reactivity to alcohol-related and emotional cues in alcohol dependent subjects following a single dose of the opioid receptor modulator nalmefene. The study will be done in a cross over design with nalmefene versus placebo.
Phase:
Early Phase 1
Details
Lead Sponsor:
Central Institute of Mental Health, Mannheim
Collaborator:
Lundbeck GmbH, Ericusspitze 2, 20457 Hamburg
Treatments:
Ethanol
Nalmefene
Naltrexone