Single and Multiple Ascending Dose Study of MTR-601 in Healthy Individuals
Status:
Recruiting
Trial end date:
2024-05-01
Target enrollment:
Participant gender:
Summary
To assess the safety and tolerability of single and multiple doses of MTR-601 in normal
healthy volunteers under fed and fasted conditions.
To evaluate the plasma and urine pharmacokinetics (PK) of MTR-601. To evaluate the
pharmacodynamic (PD) effects of MTR-601 on muscle strength and muscle accumulation of MTR-601
by muscle biopsy and other potential mechanistic, predictive and PD markers of MTR-601.