Overview

Single Dose of Furosemide to Improve Respiratory Distress in Moderate to Severe Bronchiolitis

Status:
Completed
Trial end date:
2016-04-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to assess if administration of an early single dose of a diuretic (furosemide) to children with moderate to severe bronchiolitis can reduce extravascular lung water in an effort to reduce respiratory rate, retractions, intubations, and length of stay.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Northwell Health
Treatments:
Furosemide
Criteria
Inclusion Criteria:

- Diagnosis of Acute Bronchiolitis

- Admission required per Emergency Department Physician

Exclusion Criteria:

- No legal guardian present

- Sulfa allergy

- Patient currently on existing diuretic therapy

- Tracheostomy

- Mild respiratory distress (not requiring admission)

- Hypotension / Hemodynamic Instability (defined by age specific criteria at time of
intervention)

- Supplemental Oxygen at home

- History of Dialysis / Renal Disease

- Those enrolled in another drug interventional study