Overview

Single Dose Steroid Before Thyroidectomy for Benign Disease to Improve Postoperative Nausea, Pain, and Vocal Function

Status:
Unknown status
Trial end date:
2012-10-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to evaluate the efficacy of 8 mg of dexamethasone administered prior surgery, to reduce pain, postoperative nausea and vomiting and to improve vocal function after thyroidectomy for benign disease.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Ospedale Misericordia e Dolce
Treatments:
BB 1101
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Pharmaceutical Solutions
Criteria
Inclusion Criteria:

- Age > 18 years

- Patients undergoing thyroidectomy

Exclusion Criteria:

- Patients who had received antiemetic therapy within 48 hours before surgery

- Patients with depression

- Chronic pain disorder

- Insulin-dependent diabetes mellitus

- History of severe and/or repeated PONV after previous minor surgery, that led to
change from standard anesthetic protocol

- Pregnancy

- Age < 18 years

- Patients who had known malignant disease or had undergone previous thyroid or neck
surgery