Single Dose Escalation and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4
Status:
Completed
Trial end date:
2017-02-01
Target enrollment:
Participant gender:
Summary
A phase one study of the safety, tolerability, and pharmacokinetics of a new oxazolidinone
antibiotic. Cohorts of healthy adults (female and male) will participate in:
single dose escalation study of increasing doses of MRX-4 given by mouth others will
participate in multiple dose escalation cohorts of MRX-4 given twice daily by mouth.
other cohorts of subjects will participate in the study to evaluate the impact of concomitant
food or Omeprazole on safety, tolerability and pharmacokinetics of MRX-4