Overview

Single Bolus Dose of Ketodex Versus Ketofol For Prevention Of Emergence Agitation In Adults Undergoing Nasal Surgeries

Status:
Completed
Trial end date:
2019-11-23
Target enrollment:
0
Participant gender:
All
Summary
- emergence agitation is seen in around 68% after nasal surgeries. Agitated patients needs more staff and nurses to control their abnormal movement which leads to self extubation , removal of catheters and bruises in the extremities. - Dexmedetomidine, ketamine, propofol intravenous infusion and other agents was used to prevent EA . Recently, ketodex is found to reduce the incidence and severity of EA . - We aim to compare single bolus dose of Ketodex Versus Ketofol For Prevention Of emergence Agitation in adults undergoing nasal surgeries.
Phase:
Early Phase 1
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Zagazig University
Treatments:
Dexmedetomidine
Ketamine
Propofol
Criteria
Inclusion Criteria:

- Patient acceptance.

- Both gender.

- Age (21-60) years old.

- patient with Body Mass Index (BMI) (25-35kg/m²).

- American Society of Anesthesiologist (ASA) I / II

- Adult patient scheduled to elective nasal surgeries

Exclusion Criteria:

- - Patient with difficult airway (mallampati III,IV).

- Altered mental status (psychiatric and anxiety disorder).

- Post traumatic stress disorders.

- History of allergy to study drugs.

- Patient on sedative or hypnotic medication.

- Patients with chronic pain or on painkiller.

- Patients with severe hepatic or kidney impairment.

- Patients having a history of thyrotoxicosis, hypertension, cardiac , chest or
neurological disease.

- Patient receiving B agonist.

- Pregnant or breast feeding female.