This research study seeks to find new ways to treat people with Waldenstrom's
Macroglobulinemia (WM). The study is for participants with slow growing WM who otherwise
might not need therapy for at least 3-6 months. Simvastatin is a drug approved by the FDA for
lowering cholesterol. In test tube studies the study drug appears to have direct anti-cancer
effect against WM tumor cells and mast cells.