Simvastatin as an Augmentation Treatment for Treatment Resistant Depression: Randomized Controlled Trial.
Status:
Completed
Trial end date:
2021-06-30
Target enrollment:
Participant gender:
Summary
In this double blind, randomized placebo controlled trial we aim to determine the efficacy of
simvastatin as an add-on treatment for treatment resistant depression. We will recruit 150
people with treatment-resistant depression with the aim of determining whether the addition
of simvastatin (20mg daily) to treatment as usual (TAU) for 12 weeks leads to an improvement
in depressive symptom compared with placebo added to TAU.