Simvastatin Effect on Inflammation and Endothelial Function After Myocardial Infarction
Status:
Completed
Trial end date:
2009-05-01
Target enrollment:
Participant gender:
Summary
During myocardial infarction, inflammatory response may negatively influence ventricle wall
remodeling as well as endothelium-dependent vasomotor function in the coronary and systemic
arterial systems. Statins have been consistently proved to attenuate inflammation and improve
endothelial function. In this study, we tested the effect of different doses of statin on
inflammatory response and endothelium-dependent vasodilation.