Overview

Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal Dialysis

Status:
Unknown status
Trial end date:
2006-02-01
Target enrollment:
0
Participant gender:
All
Summary
This study will analyse the effect of simvastatin on endothelium dependent venodilation in chronic renal failure patients treated by peritoneal dialysis. The hypothesis is that patients will have a greater endothelium dependent venodilation after four months of simvastatin use.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Federal University of São Paulo
Treatments:
Simvastatin
Criteria
Inclusion Criteria:

- end stage renal failure

- peritoneal dialysis

- LDL cholesterol > 100mg/dL

- > 18 years and < 80 years

Exclusion Criteria:

- using statin or nitrate

- liver disease

- diabetes mellitus