Simplified Insulin Protocol Using Lantus in Elderly

• Status: Completed
• Trial end date: 2015-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to find out if simplifying your diabetes treatment by decreasing number of insulin injections, with the help of a long acting insulin called glargine, can decrease the episodes of low blood glucose.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Joslin Diabetes Center
• Collaborator: Sanofi
• Treatments: Insulin; Insulin Glargine

Criteria

Inclusion Criteria:

• Age 70 years or older

• Diagnosis of diabetes mellitus Type II

• At least 2 (short-acting or mixed) insulin injections per day

• At least 1 episode of hypoglycemia (glucose value <70) on screening CGM

Exclusion Criteria:

• Patients with the following illnesses in the past 12 months Myocardial infarction Angina Coronary artery bypass grafting Percutaneous transluminal coronary angiography Cerebrovascular event (stroke, TIA)

• Active liver disease (history of cirrhosis or LFT > 3 times normal)

• On dialysis or with severe renal dysfunction (creatinine clearance <20 ml/min)

• Malignancy that limits life span to less than 18 months

• Patients seen in the geriatric clinic who already have simplified regimen as proposed in the study