Simplified Drug Regimens for HIV Patients in ACTG 388 or Patients Who Responded to A First Potent Combination Regimen
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
ACTG 388 was a clinical trial that compared three- and four-drug anti-HIV drug regimens and
demonstrated the effectiveness of a three-drug regimen. This study will compare the ability
of two different three-drug anti-HIV drug regimens to reduce levels of HIV in the blood. The
study will also evaluate whether patients discontinue the regimens because of drug side
effects.
Phase:
N/A
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Treatments:
Didanosine Efavirenz HIV Protease Inhibitors Lamivudine Lamivudine, zidovudine drug combination Lopinavir Protease Inhibitors Ritonavir Stavudine Zidovudine