Overview
Sildenafil Citrate of in Vitro Fertilization After Multiple IVF Failures Attributed to Poor Endometrial Development
Status:
Unknown status
Unknown status
Trial end date:
2017-08-10
2017-08-10
Target enrollment:
0
0
Participant gender:
Female
Female
Summary
The aim of this study is to evaluate the effect of sildenafil citrate on endometrial development in women with history of recurrent implantation failure after IVFPhase:
Phase 4Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Ain Shams UniversityTreatments:
Citric Acid
Sildenafil Citrate
Criteria
Inclusion Criteria:- (1) cases of infertility, older than 20 years of age and not older than 40 years.
- (2) Body mass index (BMI):20-29.
- (3) women have experienced two or more implantation failure attributed to inadequate
endometrial development.
Exclusion Criteria:
- (1) Uterine abnormalities (e.g. septate, bicornuate and fibroid uterus, Asherman
Syndrome).
- (2) Any contraindication to sildenafil citrate or any of the components of its
formulation including:
- Concurrent use of organic nitrites and nitrates.
- Severe hepatic impairment.
- Severe renal impairment.
- Hypotension.
- Recent stroke or heart attack.