Overview

Side Effects to FOLFOXIRI + Tocotrienol/Placebo as First Line Treatment of Metastatic Colorectal Cancer

Status:
Active, not recruiting

Trial end date:
2025-03-01

Target enrollment:

Participant gender:

Summary

Treatment with FOLFOXIRI (5-fluorouracil, oxaliplatin, irinotecan) can be effective, but it has serious side effects, which may require hospitalization. The purpose of this study is to investigate whether the addition of tocotrienol can reduce the side effects to FOLFOXIRI otherwise leading to hospitalization.

Phase:

Phase 2

Details

Lead Sponsor:

Vejle Hospital

Treatments:

Calcium, Dietary
Fluorouracil
Irinotecan
Leucovorin
Levoleucovorin
Oxaliplatin
Tocopherols
Tocotrienols
Vitamin E