Short vs Prolonged Antibiotic Treatment for Hospitalized Hemato-oncology Patients With Febrile Neutropenia
Status:
Unknown status
Trial end date:
2017-07-01
Target enrollment:
Participant gender:
Summary
Neutropenic fever is a life threatening condition that is not rare in patients suffering from
hematologic disorders, and of paramount importance to early and effective treatment. In this
trial we concentrate on hospitalized patients with hematologic malignancies who develop
neutropenic fever.
In recent years, several studies were conducted to examine possible changes in the
conventional empirical treatment, assuming that administration of the antibiotics in a
prolonged infusion would allow for a greater fT > MIC that will lead to a better efficacy.
These studies were carried out in different populations and there is only limited information
about the importance of continuous infusion therapy in patients with hematologic diseases
with neutropenic fever.
Research goals: The main goal is to compare between two groups of hematologic patients with
neutropenic fever, The first group will receive antibiotic therapy in extended infusion, and
the second (control) group will receive the treatment in a fixed time.