Short-Term Androgen Priming Before COS Using Aromatase Inhibitor and hCG During Early-Follicular-Phase GnRH Antagonist Administration - a Randomized Controlled Trial

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

We want to investigate if early follicular phase downregulation and androgen priming, by use of GnRH antagonist, aromatase inhibitor and hCG before COH in a short protocol, shows signs of improvement compared to standard short antagonist protocol

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rigshospitalet, Denmark
• Treatments: Androgens; Aromatase Inhibitors

Criteria

Inclusion Criteria:

• Indication and wish for IVF/ICSI treatment

• Womens age 20-39 years (both inclusive)

• Regular menstrual cycle within normal range

• Body Mass Index: 18-30 kg/m2 (both inclusive)

• Negative pregnancy test before treatment

• A maximum of 3 earlier IVF/ICSI treatments that did not result in pregnancy

Exclusion Criteria:

• serious systemic disease

• Presence of polycystic ovarian syndrome (PCOS)

• Earlier poor response with less than 4 mature follicles

• Earlier participation in the investigation