Short Course Glucocorticoid Treatment for PTSD

• Status: Completed
• Trial end date: 2009-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate if a 2-wk course of 20mg/day of oral prednisone in addition to standard care will result in reduced PTSD symptoms or symptom severity compared to placebo

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Wisconsin, Madison
• Treatments: Prednisone

Criteria

Inclusion Criteria:

• Must meet Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria for PTSD w/ symptom exacerbation (CAPS score ≥ 50)

• Stable on other psychotropic meds x1 month

Exclusion Criteria:

• Current or past history of bipolar, schizophrenic, or other psychotic disorder

• Organic mental disorder

• Alcohol or substance abuse in last 3 months

• Clinically significant hepatic or renal disease or other acute or unstable medical condition

• Chronic obstructive pulmonary disease (COPD), asthma, uncontrolled diabetes, rheumatologic diseases