Shivering Treatment After Cesarean Delivery: Meperidine vs. Dexmedetomidine

• Status: Completed
• Trial end date: 2020-08-20
• Target enrollment: 0
• Participant gender: Female

Summary

Comparing two treatments for shivering after cesarean delivery for labor dystocia under epidural anesthesia.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
• Treatments: Dexmedetomidine; Meperidine

Criteria

Inclusion Criteria:

• Term > 37 weeks

• American Society of Anesthesiologists Physical Status (ASA PS) I, II

• Weight < 115 kg

• Functional epidural in situ

• In labor requiring cesarean delivery

• Class III or IV shivering on the Crossley and Mahajan standardized shivering scale between five minutes after the baby's birth to the end of the cesarean section

Exclusion Criteria:

• Refusal of the patient and/or the anesthesiologist

• Misunderstanding of the protocol

• Known allergy or contraindication to one of the study drugs

• Emergency cesarean delivery

• American Society of Anesthesiologists Physical Status III, IV, V

• Severe heart, liver or kidney disease,

• Preeclampsia

• Patient taking monoamine oxydase inhibitors

• Sleep apnea

• General anesthesia