Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

• Status: Recruiting
• Trial end date: 2023-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

The researchers are trying to determine whether ovarian hormones are associated with aging processes and with the risk of developing Alzheimer's disease in women.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mayo Clinic
• Collaborator: National Institute on Aging (NIA)
• Treatments: Corticosterone

Criteria

Inclusion Criteria:

• Women who lived in Olmsted County, Minnesota between 1988 and 2007

• Currently aged 55 years and older

• More than six months post chemotherapy or major surgery requiring general anesthesia

• Willing and able to sign informed consent

Exclusion Criteria:

• Not able to read and speak English

• In hospice

• Claustrophobic

• If undergoing Tau imaging, cannot have QT Prolongation