Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
Status:
Completed
Trial end date:
2012-10-25
Target enrollment:
Participant gender:
Summary
The purpose of this study is to find out why women's arteries stiffen as they go through
menopause, and how this is affected by estrogen loss. We believe that arteries stiffen with
the loss of estrogen because of "oxidative stress," the production of molecules that can
damage cells and tissues in the body, and because the arteries lose their ability to expand,
or dilate.