Sex Differences in Risk for Alcohol Abuse

• Status: Recruiting
• Trial end date: 2022-02-28
• Target enrollment: 0
• Participant gender: All

Summary

This study will determine the neural and hormonal mechanisms underlying sex differences in sensitivity to the disinhibiting effects of alcohol in heavy drinkers.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Jessica Weafer
• Collaborator: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
• Treatments: Ethanol

Criteria

Inclusion Criteria:

• heavy drinking

• Alcohol Use Disorder Identification Test score above 7

• right-handed

• BMI between 19 and 26

• high school education

• fluent in English

• women must have regular menstrual cycles

• not using hormonal contraceptives

Exclusion Criteria:

• drug use disorder (SCID, DSM-5), other than nicotine or caffeine

• meets withdrawal criteria

• history of physical or psychiatric disease

• contraindication for fMRI

• pregnant or breastfeeding

• smoking more than 5 cigarettes per day