Overview

Sex, Aging and Antiretroviral Pharmacokinetics

Status:
Completed
Trial end date:
2012-05-01
Target enrollment:
Participant gender:
Summary
The purpose of this research study is to learn about levels of antiretroviral drug levels and response to HIV virus in the genital tract of women who are post-menopausal. The investigators in this study think that the levels of hormones post-menopausal HIV-infected women may have in their bodies may affect the levels of antiretroviral drug, and therefore affect how much HIV virus they have in their bodies. Since women who have already gone through menopause have different levels of hormones, such as estrogen, than women who are pre-menopausal, the investigators would like to check the levels of antiretroviral drugs in their blood, their genital secretions, and their genital tissue.
Details
Lead Sponsor:
Kristine Patterson, MD
Collaborator:
National Institute of Allergy and Infectious Diseases (NIAID)
Treatments:
Atazanavir Sulfate
Efavirenz
Emtricitabine
Etravirine
Lamivudine
Lopinavir
Maraviroc
Raltegravir Potassium
Ritonavir
Tenofovir
Zidovudine