Sevoflurane in Cardiac Surgery

• Status: Completed
• Trial end date: 2011-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Patients undergoing high risk cardiac surgery (combined CABG and valvular procedures) will be randomized to receive a total intravenous anesthesia or an anesthesia plan with sevoflurane.

The investigators want to document whether the cardioprotective properties of volatile agents could translate in an improved outcome after cardiac surgery in high risk patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Università Vita-Salute San Raffaele
• Treatments: Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• age >18 years

• written informed consent

• scheduled procedures

Exclusion Criteria:

• ongoing acute myocardial infarction

• cardiac troponin >1 ng/ml

• previous unusual response to an anesthetic

• use of sulfonylurea, theophylline or allopurinol

• thoracotomy