Sevoflurane Protective Effect on Ischemia-reperfusion Injury. Multicenter, Randomized Controlled Trial
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
This study aimed to evaluate the possible protective effect of anesthetic technique
balanced(with sevoflurane) compared with total intravenous anesthetic technique
(propofol,remifentanil). The hypothesis is that the Sevoflurane may exert protective effect
in regard to the ischemia-reperfusion injury induced on the microsurgical breast free flap
during transfer to receiving area. The investigators will evaluate the continuous flap tissue
oximetry and the level of biochemical markers.