Sevoflurane Protective Effect on Ischemia Reperfusion Injury in Microvascular Surgery

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

This study aimed to evaluate the possible protective effect of anesthetic technique balanced (BAL) compared to total intravenous anesthetic technique (TIVA-TCI) in ischemia reperfusion injury in microvascular flap in plastic surgery. The investigators will evaluate the viability of the flap using tissue oximetry monitoring and the level of biochemical markers in a circle at the end of the intervention.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Regina Elena Cancer Institute
• Treatments: Propofol; Remifentanil; Sevoflurane

Criteria

Inclusion Criteria:

• age > 18 yr

• ASA (American Society of Anesthesiology) I-II

Exclusion Criteria:

• Known unusual reaction to anesthetic drugs

• Evaluation of anesthesia increased risk for malignant hyperthermia.

• History of vascular disease.

• History of bleeding diathesis.

• Tabagism