Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial
Status:
Recruiting
Trial end date:
2022-02-01
Target enrollment:
Participant gender:
Summary
SPEED is a three arm interventional trial nested within a cohort (Trials Within Cohorts or
TWiCs design). This tests more aggressive early therapy in patients newly diagnosed with
moderate to severe PsA. Arm 1 will receive standard step up therapy in the cohort and act as
the control group. Arm 2 will receive early combination conventional synthetic disease
modifying anti-rheumatic drugs (csDMARDs). Arm 3 will receive early tumour necrosis factor
(TNF) inhibitor therapy.