Overview

Severe Aortic Stenosis and Acquired Von Willebrand´s Disease: The Impact of Desmopressin in Valve-Replacement Surgery

Status:
Completed
Trial end date:
2010-02-01
Target enrollment:
Participant gender:
Summary
Acquired Von Willebrand disease (type 2A) has been described in patients with severe aortic stenosis, the association of aortic stenosis and Digestive bleeding due to this phenomena has received the name of Heye´s syndrome. We propose that administering Desmopressin (DDAVP) in patients scheduled to aortic valve replacement surgery will reduce blood loss and transfusion rate. this was a pilot study
Phase:
Phase 4
Details
Lead Sponsor:
Pontificia Universidad Catolica de Chile
Collaborator:
Ferring Pharmaceuticals
Treatments:
Deamino Arginine Vasopressin