Serotonin-norepinephrine Reuptake Inhibitor in Prophylaxis of Depression Following Fragility Fractures
Status:
Not yet recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
The goal of this pilot study is to learn about the feasibility about prescribing
anti-depressants at discharge in patients aged 50 years and older with a lower extremity
fragility fracture. The main questions it aims to answer are:
- What are the obstacles to enrolling patients and prescribing anti-depressants among
older adults?
- Is it possible to start prescribing SNRI medication upon discharge?
- What is the prevalence of depressive symptoms amongst patients with different types of
injuries and weightbearing status?
- What is a transition of care plan for patients who have geriatric depression and require
further care?
Participants will:
- Undergo screening using the Geriatric Depression Scale
- Start on Duloxetine 30mg daily at time of discharge
- Report medication compliance and complete re-screening monthly
- Complete patient reported outcome measures and 3 months, 6 months, and 1 year
- Receive a referral to behavioral health, primary care, or psychiatrist for evaluation if
they screen positive at any timepoint