Serotonin Selective Reuptake Inhibitor (SSRI) Effects on Cerebral Connectivity in Acute Ischemic Stroke

• Status: Recruiting
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Fluoxetine action on cerebral connectivity changes in acute ischemic stroke patients

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Toulouse
• Treatments: Fluoxetine; Serotonin

Criteria

Inclusion Criteria:

• First-ever ischemic stroke

• Cortical or subcortical stroke

• National Institute of Health Stroke Scale NIHSS>12 or motor NIHSS>6 at inclusion

• MRI-proved ischemic stroke

Exclusion Criteria:

• pregnant or breast-feeding women

• alcoholism

• ongoing Selective Serotonin Reuptake Inhibitor treatment or interruption < 1 month

• allergic reaction after SSRI administration

• MRI contraindication

• NIHSS>22

• Severe aphasia

• Coma