Sequential and Hybrid Therapies for H Pylori Infection
Status:
Completed
Trial end date:
2010-05-01
Target enrollment:
Participant gender:
Summary
Primary: To evaluate efficacy of 14 day 2-phase sequential therapy given in two forms. One in
which the first component consists of a proton pump inhibitor and amoxicillin given for 7
days followed by the PPI, clarithromycin and metronidazole for 7 days. The alternate will be
similar with the exception that the amoxicillin will be continued throughout the 14 days. The
secondary endpoint is to evaluate the effectiveness of therapy in relation to antibiotic
resistance.
Phase:
Phase 4
Details
Lead Sponsor:
Kaohsiung Veterans General Hospital.
Collaborators:
Baylor College of Medicine Kaohsiung Medical University