Sequential Versus Quadruple Therapy in the Second-line Treatment
Status:
Unknown status
Trial end date:
2020-12-31
Target enrollment:
Participant gender:
Summary
Objectives: A recent randomized trial showed that 14-day sequential therapy containing high
dose proton pump inhibitor was higher than 95% in the first line treatment. However, whether
the 14-day sequential therapy is more effective than 10-day bismuth quadruple therapy remains
unknown. Therefore, the investigators aimed to compare the eradication rates and long term
re-infection rates of sequential therapy for 14 days versus bismuth quadruple therapy for 10
days in the second line treatment.