Sequential Therapy Versus Quadruple Therapy in H. Pylori Eradication
Status:
Unknown status
Trial end date:
2019-12-01
Target enrollment:
Participant gender:
Summary
The investigators aimed to
1. compare the eradication rates and long term re-infection rates of sequential therapy for
14 days versus bismuth quadruple therapy for 10 days in the first line and second line
treatment
2. assess the impact of antibiotic resistance and CYP2C19 polymorphism on the eradication
rate of these regimens
3. assess the impact of these eradication regimens on the antibiotic resistance and
microbiota of the gut flora
4. assess the impact of eradication therapy on the metabolic factors
Phase:
Phase 4
Details
Lead Sponsor:
National Taiwan University Hospital
Collaborators:
Chiayi Christian Hospital E-DA Hospital Kaohsiung Medical University Mackay Memorial Hospital National Taiwan University Hospital Hsin-Chu Branch Taipei Veterans General Hospital, Taiwan