Overview

Sensory Examination and Pharmacological Modulation of Oral Hyperexcitability in Patients With Atypical Odontalgia and Matched Healthy Controls

Status:
Completed

Trial end date:
2005-10-01

Target enrollment:

Participant gender:

Summary

This project examines experimental pain and chronic pain in the mouth, specifically the condition called atypical odontalgia (AO:atypical toothpain). In 16 patients with AO and 16 healthy persons, capsaicin (chili-pepper) is applied to the gingiva to cause pain. This pain is evaluated by the participants. In three sessions, 3 different medications are tested for effect on the pain. The medications are fentanyl, S-ketamine and placebo-treatment (saline). The aim is to know more about pain mechanisms in AO in order to develop an effective treatment.

Phase:

Phase 4

Details

Lead Sponsor:

University of Aarhus

Collaborator:

Danish Pain Research Center

Treatments:

Esketamine
Fentanyl
Ketamine