Semaglutide's Efficacy in Achieving Weight Loss for Those With HIV
Status:
Not yet recruiting
Trial end date:
2024-07-01
Target enrollment:
Participant gender:
Summary
The prevalence of obesity is rising worldwide, both in low- and high-income countries,
including people with HIV (PWH). Semaglutide's efficacy in achieving weight loss in obese PWH
is still unexplored. The aim of this study is to assess the efficacy and safety of
semaglutide in achieving greater weight loss compared to diet and excercise alone in obese
PWH and to explore the effect of semaglutide on the immune function, markers of immune
activation, viral reservoir, markers of glucose and lipid metabolism and gut microbiome.
Phase:
N/A
Details
Lead Sponsor:
University College Dublin
Collaborators:
Rush University Medical Center University of Copenhagen