Overview

Selinexor in Treating Patients With Relapsed Small Cell Lung Cancer

Status:
Terminated
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
This phase II trial studies how well selinexor work in treating patients with small-cell lung cancer that has returned after a period of improvement. One specific way cancer cells continue to grow is by getting rid of certain proteins called "tumor suppressor proteins: that would normally cause cancer cells to die. Selinexor works by trapping "tumor suppressing proteins" within the cell and may cause the cancer cells to die or stop growing.
Phase:
Phase 2
Details
Lead Sponsor:
Erin Bertino
Collaborators:
Karyopharm Therapeutics Inc
Karyopharm Therapeutics, Inc