Overview

Selinexor in Myelofibrosis Refractory or Intolerant to JAK1/2 Inhibitors

Status:
Recruiting
Trial end date:
2025-03-14
Target enrollment:
Participant gender:
Summary
This is a phase II, open label, prospective, single-arm study evaluating the efficacy and safety of selinexor in patients with PMF or secondary MF (PPV-MF or PET-MF) who are refractory or intolerant to ruxolitinib and/or any other experimental JAK1/2 inhibitors.
Phase:
Phase 2
Details
Lead Sponsor:
University of Utah
Collaborator:
Karyopharm Therapeutics Inc