Selegiline Patch for Treatment of Nicotine Dependence

• Status: Completed
• Trial end date: 2011-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Relapse to smoking is a common problem affecting smokers who seek treatment. The purpose of this study is examine whether selegiline, given in the form of a skin patch, is effective in stopping smoking.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Stanford University
• Collaborator: National Institute on Drug Abuse (NIDA)
• Treatments: Nicotine; Selegiline

Criteria

Inclusion Criteria:

• Smokes greater than 20 cigarettes per day

Exclusion Criteria:

• History of Parkinson's disease, high blood pressure, or severe liver or kidney disease

• Current substance abuse

• Mental illness

• Skin conditions that could interfere with patch use

• Using antidepressant medications (e.g., levodopa/carbidopa, methyldopa, or any MAO inhibitor)

• Pregnant or breastfeeding