Selective Thromboembolism Prophylaxis After Arthroplasty

• Status: Completed
• Trial end date: 2018-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Asian populations have a lower rate of high-risk gene mutations of venous thrombosis, which means a reasonable perioperative anticoagulant management after hip or knee arthroplasty for Caucasian populations may be too excessive for Asians. So, individual patient risk assessment, rather than a "blanket policy", is considered the best thromboembolism prophylaxis for Asians.The purpose of this study was to evaluate the effectiveness and safety of selective thromboembolism prophylaxis compared with conventional thromboembolism prophylaxis by risk stratification with thromboelastography (TEG) after joint arthroplasty for Asian populations.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Guangdong General Hospital; Guangdong Provincial People's Hospital
• Treatments: Anticoagulants; Dalteparin; Heparin, Low-Molecular-Weight

Criteria

Inclusion Criteria:

• over 18 years of age,

• ASA Ⅰ-Ⅱ grade,

• BMI <40Kg / M ^ 2

• Underwent total knee arthroplasty/ total hip arthroplasty in Guangdong General Hospital

• consent to enroll in this study

Exclusion Criteria:

• history of VTE, preoperative infection, preoperative coagulation

• liver and kidney function existed clinically abnormalities

• history of tumor

• history of vascular surgery

• heart infarction or cerebral infarction within 6 months

• history of lower extremity surgery within 3 months