Selection of Antibiotic Resistance by Azithromycin and Clarithromycin in the Oral Flora
Status:
Completed
Trial end date:
2003-10-01
Target enrollment:
Participant gender:
Summary
Resistance to antibiotics is a major public-health problem and studies linking antibiotic use
and resistance have shown an association not a causal effect. Utilizing the newer macrolides,
azithromycin and clarithromycin that are commonly prescribed for respiratory infections, we
investigated the direct impact of antibiotic exposure on resistance at the individual level.