Sedation in ICU Patients With Mechanical Ventilation
Status:
NOT_YET_RECRUITING
Trial end date:
2026-07-30
Target enrollment:
Participant gender:
Summary
Sedatives are the mostly common prescription for patients with mechanical ventilation due to the disease or therapies.
Ciprofol is a new intravenous anesthetic agent transformed from propofol, and has a similar sedative effect of propofol in previous study.
Whether ciprofol is safe and effective similar with propofol for sedation in ICU patients with mechanical ventilation? Therefor, a multi-center, double-blind, randomized control trial was conducted with a noninferiority design, to compared the rate of successful sedation without hypotension of sedation by ciprofol or propofol in ICU patients with mechanical ventilation.
A Multi-Center, Double-Blind, Randomized Controlled Trial will be launched to evaluate the efficacy and safety of ciprofol versus propofol for sedation in ICU patients with mechanical ventilation.
Phase:
NA
Details
Lead Sponsor:
Zhongda Hospital
Collaborators:
Anhui provincial chest hospital Fifth Affiliated Hospital of Xinjiang Medical University First Affiliated Hospital of Kunming Medical University First Affiliated Hospital of Suzhou Medical College First Affiliated Hospital of the University of Science and Technology of China (Anhui Provincial Hospital) First Affiliated Hospital of the Xi'an Jiaotong University First Affiliated Hospital, Sun Yat-Sen University First People's Hospital of Hangzhou Hebei Medical University Fourth Hospital Henan Provincial People's Hospital Huai'an First People's Hospital Jiangsu Subei People's Hospital Jiangxi Provincial People's Hopital Jinan City People's Hospital Renmin Hospital of Wuhan University Second Affiliated Hospital of Suzhou University Sichuan Academy of Medical Sciences Suqian First Hospital Tai'an City Central Hospital The First Affiliated Hospital of Air Force Medicial University The First Affiliated Hospital of Nanchang University The First People's Hospital of Lianyungang The first People's Hospital of Yancheng City The First People's Hospital of Zunyi The Guangxi Zhuang Autonomous Region People's Hospital The Ninth People's Hospital of Suzhou The Third Bethune Hospital of Jilin University Xuzhou Central Hospital Xuzhou Medical University Hospital Zhongnan Hospital Zhongnan University Xiangya Second Hospital