Sedation With Dexmedetomidine During Cardiac Catheterization
Status:
Terminated
Trial end date:
2013-04-01
Target enrollment:
Participant gender:
Summary
Clinical dose escalation drug trial to evaluate the effect of 3 different doses of
dexmedetomidine on the pulmonary vascular bed in pediatric subjects with elevated pulmonary
vascular resistance (PVR). The study will be conducted in 2 parts, with part 1 incorporating
stopping rules to optimize safety of the drug in this population. The second part of this
study will evaluate if the lowest safest dose, as determined in part 1, is adequate to
provide effective sedation during a cardiac catheterization procedure.