Sedation During Bronchoscopy:Dexmedetomidine vs Alfentanil
Status:
Completed
Trial end date:
2014-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to find the best sedation necessary for patients undergoing
bronchoscopy. Patients are randomized to three different regimes of sedation during
bronchoscopy were studied:
1. - Group standard/control: local anesthesia only(C)
2. - Group alfentanil + local anesthesia(A)
3. - Group dexmedetomidine + local anesthesia(D) The primary endpoint is the bronchoscopy
score. Secondary endpoints are: Level of sedation and tolerance bronchoscopy
examination. Measured parameters on the safety of examination are: the lowest
saturation, needs to supplemental oxygen, amnesia , choking sensation or chest pain and
if the patient is ready or not to undertake bronchoscopy second time in his life if
necessary. Endtidal CO2, Respiratory rate, Blood pressure, Heart rate, level of oxygen
are collected every 5 minutes before, during and after the bronchoscopy.