Overview

Secukinumab in Active Non-segmental Vitiligo

Status:
Completed
Trial end date:
2019-02-22
Target enrollment:
Participant gender:
Summary
Vitiligo is an acquired autoimmune skin disorder which leads to cutaneous depigmentations. A lot of progress has been made to unravel the pathophysiology of vitiligo. Several independent studies confirmed the elevated values of IL-17 in the serum of vitiligo patients and higher IL-17 values have been linked to a higher affected body surface area and a longer disease duration. The study will be a pilot trial with secukinumab in patients with active, non-segmental vitiligo. All patients will receive the active compound (= no placebo arm) as the purpose of the study is to investigate the potential efficacy of secukinumab in vitiligo.
Phase:
Phase 4
Details
Lead Sponsor:
University Hospital, Ghent
Collaborator:
Novartis