Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)
Status:
Recruiting
Trial end date:
2022-06-01
Target enrollment:
Participant gender:
Summary
This is a treatment guideline for a second or greater allogeneic hematopoietic stem cell
transplant (HSCT) using a reduced intensity conditioning (RIC) in patients with non-malignant
or malignant diseases. This regimen, consisting of busulfan, fludarabine, and low dose total
body irradiation (TBI), is designed to promote engraftment in patients who failed to achieve
an acceptable level of donor-derived engraftment following a previous allogeneic HCT.