Overview

Second-Line Uterotonics in Postpartum Hemorrhage: A Randomized Clinical Trial

Status:
Recruiting
Trial end date:
2022-03-01
Target enrollment:
Participant gender:
Summary
The aim of this study is to evaluate in a randomized fashion the comparative efficacy of two second-line medications, methylergonovine and carboprost for treating atonic postpartum hemorrhage (PPH). The investigators hypothesize that administration of methylergonovine will produce superior uterine tone to carboprost in atonic PPH.
Phase:
Phase 4
Details
Lead Sponsor:
Brigham and Women's Hospital
Treatments:
Carboprost
Carboprost tromethamine
Dinoprost
Dinoprost tromethamine
Maleic acid
Methylergonovine