Second-Line Treatments for Anovulatory Infertility in PCOS Patients
Status:
Completed
Trial end date:
2005-10-01
Target enrollment:
Participant gender:
Summary
To date, it is still unclear the potential role of laparoscopic ovarian diathermy (LOD) in
the management of polycystic ovary syndrome (PCOS)-related anovulatory infertility. Metformin
administration, alone or combined with clomiphene citrate (CC), has shown to be an effective
and attractive second-line treatment for ovulation induction in women with polycystic ovary
syndrome (PCOS) after failure of CC treatment. The aim of the present study will be to
compare in a randomized controlled fashion the efficacy of LOD with metformin plus CC
administration in the treatment of the CC-resistant PCOS patients.